Chronic Kidney Disease (CKD) – Comprehensive Management & Prevention
Chronic Kidney Disease affects millions worldwide, but early detection and expert management can significantly slow its progression.
Our kidney specialist team in Sonipat provides comprehensive CKD care tailored to your stage and needs.
What is Chronic Kidney Disease?
CKD is a progressive condition where your kidneys gradually lose their ability to filter waste and excess fluids from your blood.
What Causes CKD?
- Diabetes: The leading cause of kidney damage (diabetic nephropathy)
- High Blood Pressure: Uncontrolled hypertension damages kidney blood vessels
- Glomerulonephritis: Inflammation of kidney filtering units
- Polycystic Kidney Disease: Inherited genetic disorder
- Prolonged Urinary Obstruction: From kidney stones or enlarged prostate
- Recurrent Kidney Infections: Chronic pyelonephritis
Common Symptoms You Can Identify:
- Persistent fatigue and weakness
- Swelling in ankles, feet, or hands (edema)
- Decreased urine output or foamy urine
- Difficulty concentrating or mental fog
- Loss of appetite and unexplained weight loss
- Persistent itching and dry skin
- Muscle cramps, especially at night
- High blood pressure that’s difficult to control
When to Seek Our Expert Care
Immediate Attention Needed If You Experience:
- Sudden decrease in urine output
- Severe swelling in the legs or face
- Shortness of breath or chest pain
- Confusion or altered mental status
- Blood in urine or dark-colored urine
- Uncontrolled nausea and vomiting
Our Advanced Treatment Approach for CKD
A. Precise Diagnosis:
- Comprehensive Blood Tests: Serum creatinine, BUN, eGFR calculation, and electrolyte panel
- Urine Analysis: Protein-to-creatinine ratio, microalbuminuria testing
- Kidney Ultrasound & Imaging: Assess kidney size, structure, and blood flow
- Kidney Biopsy: When needed for definitive diagnosis
B. Personalized Medical Management:
- Blood Pressure Control: ACE inhibitors and ARBs to protect kidneys
- Blood Sugar Management: For diabetic nephropathy patients
- Anemia Treatment: Erythropoietin therapy and iron supplementation
- Bone Health Protection: Calcium, vitamin D, and phosphate binders
- Fluid & Electrolyte Balance: Customized medication to maintain homeostasis
C. Comprehensive Lifestyle Support:
- Renal Diet Planning: Low sodium, controlled protein, and potassium management
- Exercise Programs: Safe physical activity recommendations
- Smoking Cessation: Counseling and support to quit tobacco
- Stress Management: Psychological support for chronic disease management
Why Choose Primax Nephrology for CKD Management?
At Primax Gastro Institute & Superspeciality Hospital, we provide evidence-based, patient-centered CKD care that focuses on slowing disease progression and maintaining your quality of life.
- Expert Nephrologists: Board-certified kidney specialists with extensive CKD management experience
- Advanced Monitoring: Regular kidney function assessments to track progression
- Integrated Care: Coordination with diabetes, cardiology, and nutrition teams
📞 Take Control of Your Kidney Health
Don’t let CKD progress unchecked. Early intervention is key to preserving kidney function.
Consult our kidney specialists at Primax Nephrology Department – Call 9666460009 or visit our
Contact Us
page to schedule your comprehensive kidney evaluation today.
Acute Kidney Injury (AKI) – Emergency Kidney Care & Rapid Recovery
Acute Kidney Injury is a medical emergency that requires immediate expert intervention.
Our 24/7 nephrology emergency team at Primax Hospital is equipped to handle critical kidney
situations with rapid diagnosis and life-saving treatments.
Understanding Acute Kidney Injury: AKI is a sudden loss of kidney function that occurs within hours or days.
Unlike chronic kidney disease, AKI can often be reversed with prompt treatment. Our emergency nephrology team
understands the urgency and provides immediate, specialized care.
What Causes Acute Kidney Injury?
- Severe Dehydration: From vomiting, diarrhea, or inadequate fluid intake
- Severe Infections (Sepsis): Body-wide infection affecting kidney blood flow
- Medications & Toxins: NSAIDs, antibiotics, contrast dyes, or poisoning
- Sudden Blood Pressure Drop: From surgery, trauma, or heart failure
- Urinary Obstruction: Kidney stones, enlarged prostate, or tumors
- Kidney Inflammation: Acute glomerulonephritis or vasculitis
Critical Warning Signs of AKI:
- Sudden decrease in urine output (oliguria)
- Swelling in legs, ankles, or around eyes
- Persistent nausea and vomiting
- Confusion or drowsiness
- Chest pain or pressure
- Seizures (in severe cases)
- Shortness of breath from fluid buildup
When to Seek Emergency Kidney Care
IMMEDIATE EMERGENCY ATTENTION Required:
- Urine output less than 400ml in 24 hours
- Blood in urine with decreased output
- Severe swelling and difficulty breathing
- Altered consciousness or seizures
- Recent use of nephrotoxic medications with symptoms
Our Emergency AKI Treatment Protocol
A. Rapid Diagnostic Workup:
- STAT Blood Tests: Creatinine, BUN, electrolytes, and acid-base balance
- Emergency Urinalysis: To identify underlying cause
- Kidney Ultrasound: Immediate imaging to rule out obstruction
- Central Venous Pressure Monitoring: Assess fluid status
B. Intensive Medical Management:
- Fluid Resuscitation: IV fluids to restore kidney perfusion
- Medication Adjustment: Discontinue nephrotoxic drugs, dose adjustment
- Blood Pressure Support: Vasopressors if needed to maintain kidney blood flow
- Electrolyte Correction: Emergency management of dangerous potassium levels
- Acid-Base Balance: Bicarbonate therapy for severe acidosis
C. Advanced Interventions:
- Emergency Hemodialysis: For life-threatening complications (hyperkalemia, fluid overload, uremia)
- Continuous Renal Replacement Therapy (CRRT): For hemodynamically unstable patients
- Urinary Catheterization: Relief of obstruction if present
Why Choose Primax for AKI Emergency Care?
- 24/7 Nephrologist Availability: Round-the-clock expert kidney specialists
- Emergency Dialysis Ready: Immediate dialysis capability for critical cases
- Advanced ICU Support: Dedicated nephrology ICU with continuous monitoring
🚨Emergency Kidney Care Available 24/7
If you or a loved one shows signs of acute kidney injury, don’t wait.
Call our Emergency Nephrology Line: 9666460009 – Our team is ready to provide immediate life-saving kidney care.
Hemodialysis and Peritoneal Dialysis – Life-Sustaining Kidney Replacement Therapy
When kidneys can no longer filter waste effectively, dialysis becomes essential for survival. At Primax Hospital’s modern dialysis center, we provide both hemodialysis and peritoneal dialysis with the highest standards of safety, comfort, and personalized care.
Dialysis is a life-saving treatment that performs the filtering function your kidneys can no longer handle. Our dialysis team works closely with you to choose the best dialysis modality that fits your lifestyle, medical condition, and personal preferences.
When is Dialysis Needed?
- Stage 5 CKD: When eGFR falls below 15 ml/min
- Severe Fluid Overload: Unresponsive to medications
- Life-Threatening Electrolyte Imbalance: Especially high potassium
- Uremic Symptoms: Nausea, confusion, pericarditis
- Severe Metabolic Acidosis: pH imbalance affecting vital organs
Hemodialysis vs. Peritoneal Dialysis
| Feature |
Hemodialysis |
Peritoneal Dialysis |
| Location |
Dialysis center (3x/week) |
Home-based, daily |
| Duration |
4 hours per session |
Multiple short exchanges or overnight |
| Fluid Restriction |
More restrictive |
More flexible |
| Lifestyle |
Scheduled center visits |
Greater independence |
| Best For |
Patients needing supervised care |
Self-sufficient patients preferring home care |
Our Comprehensive Dialysis Services
A. State-of-the-Art Hemodialysis Center:
- 20+ Dialysis Stations: Spacious, private, and comfortable
- Latest Dialysis Machines: With online hemodiafiltration capability
- HEPA-Filtered Environment: Ultra-clean air to prevent infections
- Individual Entertainment Systems: TV and Wi-Fi at each station
- Trained Dialysis Nurses: Dedicated staff monitoring every session
- Emergency Equipment: Full resuscitation capabilities on-site
B. Peritoneal Dialysis Program:
- Comprehensive PD Training: One-on-one education for patients and caregivers
- Home Setup Support: We help establish your home dialysis area
- Regular Follow-up: Monthly clinic visits to monitor effectiveness
- 24/7 PD Helpline: Expert support whenever you need it
- Supplies Management: Coordinated delivery of dialysis solutions and supplies
Dialysis Access Management
For Hemodialysis:
- AV Fistula Creation: Gold standard permanent access
- AV Graft Placement: When a fistula isn’t feasible
- Tunneled Catheter: Temporary or permanent venous access
- Access Monitoring: Regular ultrasound surveillance
For Peritoneal Dialysis:
- PD Catheter Insertion: Minimally invasive surgical placement
- Exit Site Care Training: Preventing infections
- Catheter Troubleshooting: Expert management of any issues
Comprehensive Patient Support
- Renal Dietitian Services: Personalized meal plans, fluid management, phosphorus/potassium control, protein optimization
- Medication Management: Phosphate binders, vitamin supplements, anemia management, blood pressure control, immunizations
- Psychological Support: Counseling, family support groups, depression/anxiety management, quality of life programs
Why Choose Primax for Dialysis Care?
- Expert Nephrologists: Specialized kidney doctors overseeing all dialysis treatments
- Infection-Free Record: Stringent protocols maintain the lowest infection rates
- Flexible Scheduling: Morning, afternoon, and evening slots available
💙 Begin Your Dialysis Journey with Confidence
Whether you’re starting dialysis or seeking a better dialysis experience, we’re here to support you.
Schedule your dialysis consultation at Primax Nephrology – Call 9666460009 or book online through our Contact Us page.
Kidney Transplant Evaluation and Follow-up – Comprehensive Pre & Post-Transplant Care
A kidney transplant offers the best quality of life for patients with end-stage kidney disease. While we don’t perform transplant surgery on-site, Primax Nephrology provides complete pre-transplant evaluation, referral coordination, and lifelong post-transplant follow-up care.
Kidney transplantation is the preferred treatment for kidney failure, offering freedom from dialysis and improved life expectancy. Our transplant evaluation program ensures you’re medically, psychologically, and socially prepared for this life-changing procedure.
Who is Eligible for a Kidney Transplant?
- Patients with Stage 4-5 CKD (eGFR <20 ml/min)
- End-stage renal disease on dialysis
- Adequate cardiac and overall health status
- No active infections or cancer
- Psychological readiness and family support
- Financial resources or insurance coverage
Our Pre-Transplant Evaluation Services
A. Complete Medical Assessment:
- Cardiovascular Evaluation: Stress tests, echocardiogram, and coronary angiography if needed
- Infectious Disease Screening: HIV, hepatitis B/C, tuberculosis, CMV, EBV
- Cancer Screening: Age-appropriate screenings (mammogram, colonoscopy, PSA)
- Immunological Testing: Tissue typing, antibody screening, crossmatching
- Metabolic Assessment: Bone density, nutritional status, diabetes control
B. Living Donor Evaluation:
- Donor compatibility testing (blood type, HLA matching)
- Donor medical and psychological screening
- Donor-recipient crossmatch testing
- Coordination of paired kidney exchange if needed
C. Psychosocial Evaluation:
- Mental health assessment
- Family support system evaluation
- Financial counseling and insurance verification
- Education about transplant process and expectations
D. Pre-Transplant Optimization:
- Vaccination completion (pneumonia, hepatitis B, flu)
- Dental clearance to prevent post-transplant infections
- Smoking cessation and weight optimization
- Medication adjustment before surgery
Post-Transplant Follow-up Care
Immediate Post-Transplant (First 3 Months):
- Weekly clinic visits for monitoring
- Frequent blood tests (creatinine, tacrolimus levels, electrolytes)
- Immunosuppression medication adjustment
- Early rejection surveillance and management
- Infection prevention and screening
Long-Term Transplant Care (Lifelong):
- Monthly to quarterly follow-up visits
- Annual protocol kidney biopsies (if indicated)
- Cardiovascular risk management
- Cancer surveillance (skin, lymphoma)
- Bone health monitoring
- Medication adherence support
Why Choose Primax for Transplant Care?
- Expert Transplant Nephrologists: Specialized in pre- and post-transplant management
- Partner Network: Established relationships with top transplant centers
- Lifelong Support: Continuous care from evaluation through decades after transplant
🎯 Start Your Transplant Journey Today
If you’re considering kidney transplantation or need post-transplant care, our team is here to guide you.
Contact Primax Nephrology Transplant Program – Call 9666460009 or visit our Contact Us page to schedule your comprehensive evaluation.
Diabetic Nephropathy – Specialized Diabetes-Related Kidney Disease Management
Diabetes is the leading cause of kidney disease worldwide. At Primax Nephrology, we specialize in diabetic nephropathy management, combining expert kidney care with advanced diabetes control to preserve your kidney function and prevent complications.
Diabetic nephropathy develops when high blood sugar damages the tiny blood vessels in your kidneys over time. Early detection and aggressive management can slow or even halt the progression to kidney failure.
What Causes Diabetic Nephropathy?
- Chronic High Blood Sugar: Damages kidney filtering units (glomeruli)
- Uncontrolled Blood Pressure: Accelerates kidney damage
- Genetic Predisposition: Family history of kidney disease
- Long Duration of Diabetes: Risk increases after 5-10 years
- Smoking: Compounds vascular damage
- High Cholesterol: Contributes to kidney blood vessel damage
Early Warning Signs to Watch
- Persistent foamy or bubbly urine (protein in urine)
- Swelling in ankles, feet, hands, or face
- Increased frequency of nighttime urination
- Fatigue and weakness
- Difficulty controlling blood pressure
- Worsening blood sugar control
- Loss of appetite and nausea
When to Seek Specialized Diabetic Kidney Care
- You’ve had diabetes for 5+ years without kidney screening
- Your urine shows protein (albumin)
- Your eGFR is declining
- Blood pressure is difficult to control
- You experience unexplained swelling or fatigue
Our Comprehensive Diabetic Nephropathy Treatment
A. Aggressive Blood Sugar Management:
- Target HbA1c <7%: Personalized diabetes control strategies
- Continuous Glucose Monitoring: Advanced diabetes technology
- Insulin Optimization: Tailored insulin regimens
- Diabetes Medications: SGLT2 inhibitors (proven kidney protection)
- Endocrinology Coordination: Integrated diabetes-kidney care team
B. Kidney-Protective Medications:
- ACE Inhibitors or ARBs: First-line kidney protection (reduce proteinuria by 30-40%)
- SGLT2 Inhibitors: Dapagliflozin, empagliflozin for dual diabetes-kidney benefit
- Mineralocorticoid Receptor Antagonists: Finerenone for additional protection
- GLP-1 Agonists: Cardiovascular and kidney benefits
C. Blood Pressure Control:
- Target BP <130/80 mmHg: Strict control to slow progression
- Multiple Medication Regimens: Tailored to your needs
- Home Blood Pressure Monitoring: Daily tracking and adjustment
- Lifestyle Modifications: Low-sodium diet, weight management
D. Regular Monitoring & Early Detection:
- Quarterly Kidney Function Tests: Creatinine, eGFR, urine albumin
- Annual Comprehensive Evaluation: Including cardiovascular risk assessment
- Retinopathy Screening: Diabetes affects eyes and kidneys similarly
- Foot Care Assessment: Comprehensive diabetes complications screening
Advanced Treatments & Clinical Trials:
- Stem Cell Therapy Research: Investigating regenerative approaches
- Novel Medications: Access to latest kidney-protective drugs
- Personalized Medicine: Genetic testing to optimize treatment
- Telemedicine Monitoring: Remote glucose and BP tracking
Lifestyle & Nutrition for Diabetic Kidney Health:
(i) Specialized Renal-Diabetic Diet:
- Low-sodium meals (1500-2000 mg/day)
- Controlled carbohydrate intake for blood sugar stability
- Moderate protein (0.8 g/kg body weight)
- Potassium and phosphorus management as kidney function declines
- Personalized meal plans by our renal dietitian
(ii) Exercise Recommendations:
- 150 minutes/week of moderate activity
- Safe exercises for diabetes and kidney disease
- Blood sugar monitoring during exercise
- Supervised cardiac rehabilitation if needed
Why Choose Primax for Diabetic Nephropathy Care?
- Dual Expertise: Nephrologists and endocrinologists working together
- Proven Kidney Protection: SGLT2 inhibitors and latest treatments
- Personalized Care Plans: Tailored to your diabetes and kidney status
🛡️ Protect Your Kidneys from Diabetes Damage
Early intervention is crucial. Don’t let diabetes silently damage your kidneys.
Schedule your diabetic kidney screening at Primax Nephrology – Call 9666460009 or visit our Contact Us page today.
Hypertensive Nephrosclerosis – High Blood Pressure Kidney Damage Treatment
Uncontrolled high blood pressure is the second leading cause of kidney failure. At Primax Nephrology, we specialize in managing hypertensive nephrosclerosis, protecting your kidneys through aggressive blood pressure control and comprehensive cardiovascular-renal care.
Chronic high blood pressure damages the small blood vessels in your kidneys, reducing their filtering ability over time. This condition often develops silently over the years. Our expert team provides early detection and intensive treatment to prevent progression to kidney failure.
What Causes Hypertensive Kidney Damage?
- Chronic Uncontrolled Hypertension: Sustained BP >140/90 mmHg for years
- African American Ethnicity: Higher genetic risk
- Family History: Genetic predisposition to hypertensive kidney disease
- Diabetes + Hypertension: Synergistic kidney damage
- Smoking: Accelerates vascular damage
- Obesity: Compounds hypertension effects
Symptoms of Hypertensive Kidney Disease
- Often asymptomatic in early stages (“silent killer”)
- Headaches (especially morning headaches)
- Fatigue and weakness
- Swelling in legs or ankles
- Shortness of breath
- Chest pain (if heart is also affected)
- Blood in urine (rare, but serious sign)
When to See a Nephrologist for Hypertension
- Blood pressure consistently >140/90 despite medication
- New protein in urine (detected on routine screening)
- Declining kidney function (rising creatinine)
- Resistant hypertension (requiring 3+ medications)
- Hypertensive emergency (BP >180/120 with symptoms)
Our Comprehensive Hypertension-Kidney Treatment
A. Aggressive Blood Pressure Management:
- Target BP <120/80 mmHg: Stricter control to maximize kidney protection
- ACE Inhibitors or ARBs: First-line for kidney protection
- Multiple Drug Combinations: Tailored regimens (often 2-4 medications)
- Home BP Monitoring: Daily tracking with automatic devices
- 24-Hour Ambulatory BP Monitoring: Detect nocturnal hypertension
B. Advanced Hypertension Workup:
- Secondary Hypertension Screening: Rule out renal artery stenosis, hyperaldosteronism
- Renal Artery Doppler Ultrasound: Assess kidney blood flow
- Renin-Aldosterone Testing: Identify hormonal causes
- Sleep Apnea Evaluation: A common contributor to resistant hypertension
C. Kidney Function Monitoring:
- Regular eGFR Tracking: Every 3-6 months
- Urine Protein Assessment: Quarterly albumin-to-creatinine ratio
- Electrolyte Monitoring: Especially with multiple medications
- Cardiovascular Risk Assessment: Heart disease often coexists
Advanced Interventions for Resistant Hypertension:
- Renal Denervation: Minimally invasive procedure for resistant hypertension
- Referral to Hypertension Specialist: For complex cases
- Medication Optimization: Trial of spironolactone, hydralazine
- Sleep Study: CPAP for sleep apnea treatment
Why Choose Primax for Hypertensive Kidney Disease?
- Expert Blood Pressure Management: Specialized in resistant and secondary hypertension
- Advanced Kidney Protection: Latest evidence-based treatments to slow progression
- Cardiovascular Coordination: Integrated care for heart and kidney health
❤️ Take Control of Your Blood Pressure & Protect Your Kidneys
Don’t let high blood pressure silently damage your kidneys. Early aggressive treatment can prevent kidney failure.
Schedule your hypertension-kidney evaluation at Primax Nephrology – Call 9666460009 or book online at our Contact Us page.
Glomerulonephritis – Expert Management of Kidney Inflammation
Glomerulonephritis is inflammation of the kidney’s filtering units (glomeruli), often requiring urgent specialized care. At Primax Nephrology, our expert team provides comprehensive diagnosis and treatment for all forms of glomerular diseases, from mild to severe.
Glomerulonephritis can be acute (sudden onset) or chronic (developing over time). It may result from infections, autoimmune diseases, or unknown causes. Early diagnosis and treatment are essential to prevent permanent kidney damage.
What Causes Glomerulonephritis?
- Post-Infectious: Streptococcal throat or skin infections, bacterial endocarditis, viral infections (hepatitis B/C, HIV)
- Autoimmune Diseases: Systemic lupus erythematosus (SLE), IgA nephropathy (Berger’s disease), Goodpasture syndrome, ANCA-associated vasculitis
- Other Causes: Diabetic glomerulosclerosis, hereditary nephritis (Alport syndrome), medications and toxins
Warning Signs of Glomerulonephritis
- Pink or cola-colored urine (blood in urine)
- Foamy urine (excessive protein)
- Facial swelling (especially around eyes in morning)
- Leg and ankle swelling
- High blood pressure (sudden onset or worsening)
- Reduced urine output
- Fatigue and weakness
When to Seek Emergency Kidney Care
- Visible blood in urine with swelling
- Sudden severe swelling of face and body
- Difficulty breathing (pulmonary edema)
- Blood pressure >180/120 mmHg
- Severe reduction in urine output
- Signs of kidney failure (confusion, nausea, chest pain)
Our Comprehensive Glomerulonephritis Diagnosis
A. Advanced Diagnostic Testing:
- Urinalysis with Microscopy: Detect red blood cells, casts, and protein
- 24-Hour Urine Collection: Quantify protein loss
- Blood Tests: Complement levels, ANA, ANCA, anti-GBM antibodies
- Kidney Biopsy: Gold standard for definitive diagnosis and classification
- Imaging Studies: Ultrasound to assess kidney size and structure
B. Specialized Immunological Workup:
- Complement C3, C4 levels
- Antinuclear antibodies (ANA)
- Anti-neutrophil cytoplasmic antibodies (ANCA)
- Anti-glomerular basement membrane (anti-GBM) antibodies
- Hepatitis B, C, HIV screening
- Cryoglobulin testing
Our Treatment Protocols for Glomerulonephritis
A. Medical Management:
- Mild-Moderate Disease: ACE inhibitors or ARBs, BP control <130/80 mmHg, diuretics for edema, dietary sodium/protein restriction, cholesterol management (statins)
- Severe or Progressive Disease: High-dose corticosteroids, immunosuppressive agents (cyclophosphamide, mycophenolate, rituximab), plasmapheresis, anticoagulation if nephrotic syndrome present
B. Emergency Interventions:
- Urgent Dialysis – For severe kidney failure with fluid overload
- Pulse Steroids – For rapidly progressive GN
- Plasma Exchange – For Goodpasture syndrome or severe ANCA vasculitis
- ICU Admission – For life-threatening complications
Long-Term Management & Monitoring
- Regular kidney function monitoring (monthly to quarterly)
- Urinalysis to track proteinuria and hematuria
- Blood pressure surveillance
- Immunosuppression side effect monitoring
- Bone health protection during steroid therapy
- Infection prevention strategies
Why Choose Primax for Glomerulonephritis Care?
- Expert Glomerular Disease Specialists: Fellowship-trained in glomerulonephritis
- In-House Kidney Biopsy: Same-day biopsy with rapid pathology results
- Comprehensive Immunosuppression Management: Safe, effective treatment protocols
🔬 Get Expert Diagnosis & Treatment for Kidney Inflammation
Early diagnosis and treatment can save your kidneys from permanent damage.
Consult our glomerulonephritis specialists at Primax Nephrology – Call 9666460009 or visit our Contact Us page.
Polycystic Kidney Disease (PKD) – Genetic Kidney Disease Management
Polycystic Kidney Disease is an inherited condition causing multiple cysts to grow in the kidneys, eventually leading to kidney failure. At Primax Nephrology, we provide comprehensive PKD management, including genetic counseling, monitoring, and advanced treatments to slow disease progression.
PKD is one of the most common genetic kidney diseases, affecting about 1 in 500-1000 people. The disease causes fluid-filled cysts to develop and enlarge in both kidneys over time, gradually reducing kidney function. While there’s no cure, modern treatments can significantly slow progression.
Types of Polycystic Kidney Disease
- Autosomal Dominant PKD (ADPKD): Most common (90%), symptoms appear in 30s-40s, inherited from one parent (50% chance), progressive kidney enlargement with multiple cysts
- Autosomal Recessive PKD (ARPKD): Rare, presents in infancy/childhood, both parents must carry the gene, often more severe, associated with liver disease
Common Symptoms of PKD
- Early Stages: Often asymptomatic, mild back/flank pain, high blood pressure, microscopic or visible blood in urine
- Advanced Stages: Severe back/side/abdominal pain, frequent kidney or cyst infections, kidney stones, progressive kidney function decline, headaches, heart valve abnormalities
When to Seek PKD Specialist Care
- Family history of PKD
- Unexplained kidney enlargement on imaging
- High blood pressure at young age (<30 years)
- Recurrent kidney infections
- Declining kidney function with large kidneys
PKD Progression & Monitoring
| Stage | Age Range | Management Focus |
|---|
| Early | 20-40 years | BP control, pain management, screening |
| Moderate | 40-55 years | Intensive monitoring, consider tolvaptan |
| Advanced | 55-70 years | Dialysis preparation, transplant evaluation |
| End-Stage | Variable | Dialysis or transplant |
Our Comprehensive PKD Management
A. Genetic Testing & Counseling:
- PKD Gene Testing: Identify PKD1 or PKD2 mutations
- Family Screening: Test at-risk family members
- Genetic Counseling: Understanding inheritance patterns and family planning
- Prenatal Testing: Options for affected families
B. Regular Monitoring & Surveillance:
- Annual Kidney Function Tests: Creatinine, eGFR tracking
- Blood Pressure Monitoring: Strict BP control
- MRI or CT Imaging: Track kidney volume growth (every 1-3 years)
- Screening for Complications: Brain MRI for aneurysms, echocardiogram for heart valves, liver imaging for polycystic liver disease
C. Medical Treatment Options:
- Blood Pressure Management: Target BP <110/75 mmHg in early PKD, ACE inhibitors or ARBs, multiple medications as needed
- Tolvaptan Therapy (Jynarque): FDA-approved to slow PKD progression, blocks vasopressin receptors, requires liver function monitoring, best for rapidly progressive disease
- Pain Management: NSAIDs cautiously, opioid medications for severe episodes, cyst aspiration/sclerotherapy, surgical cyst reduction if needed
- Dietary & Lifestyle Modifications: Adequate hydration (2-3L/day), low sodium diet <2000mg/day, reduce caffeine, maintain healthy weight, avoid contact sports
Advanced Treatment Options:
- Surgical Interventions: Cyst aspiration/sclerotherapy, laparoscopic cyst decortication, nephrectomy, kidney transplantation
- Emerging Therapies: Clinical trials, combination therapies, personalized medicine based on genetic profile
Associated Conditions We Monitor:
- Cardiovascular: Hypertension (75% of PKD patients), left ventricular hypertrophy, heart valve problems
- Cerebrovascular: Brain aneurysms (10%), MRA screening for high-risk patients
- Hepatic: Polycystic liver disease, liver cyst management
Why Choose Primax for PKD Management?
- PKD Specialist Nephrologists: Extensive experience managing genetic kidney diseases
- Tolvaptan Access: One of few centers offering this breakthrough therapy
- Comprehensive Family Screening: Genetic testing and counseling services
🧬 Take Control of Your PKD Journey
Early diagnosis and proactive management can significantly slow PKD progression and delay the need for dialysis.
Schedule your PKD consultation at Primax Nephrology – Call 9666460009 or visit our Contact Us page to begin comprehensive care.
